Specialty Division

Azithromycin Tablets 500 mg

Indications:

• Acute Exacerbation Of Chronic Bronchitis
• Acute Bacterial Sinusitis 
• Community Acquired Pneumonia
• Pharyngitis/Tonsillitis
• Uncomplicated SSTI
• Urethritis / Cervicitis
• Genital Ulcer Disease 
• Uncomplicated skin & skin structure infections 

Dosage

Infants and Children : 10-30 mg/kg once a daily for 3 days.
Oral Dosage : 500 mg 3-4 times a day for 3-5 days.
Really Impaired Patients : No dosage adjustment required.

Packing : 10 Strips of 3 Tablets

Indications :

• Endometriosis  associated infertility

• Benign breast disease (chronic cystic mastitis, mastodynia)

• Menorrhagia

• Gynaecomastia

• Primary constitutional precocious puberty

• Hereditary Angioedema

• Thrombocytopenic purpura

Dosage :

Female :
Endometriosis and associated infertility :
200-800 mg daily in divided doses.
Dosage should be increased (but not to exceed 800mg per day).

Benign breast disease (chronic cystic mastitis, virginal breast hyperplasia, mazoplasia, mastodynia) :
100-400 mg daily in divided doses.

Menorrhagia :
200 mg daily for 12 weeks. Exceptional cases may need up to 400 mg daily.

Male :
Gynaecomastia :
200-800 mg daily, in divided doses.

Children:
Primary constitutional precocious puberty :
100-400 mg daily, according to patient's age and weight.

Really Impaired Patients : Not known, administer with caution.

Packing :

Indications :

• Iron deficiency anaemia including Macrocytic anaemia

• Anaemia due to excessive haemorrhage

• Anaemia associated with infections

• Anaemia associated with malignant disease

• Prevention and treatment of iron deficiency anaemia before, during and after pregnancy and during lactation

• For prophylactic therapy of iron deficiency

Dosage :

Dosage and duration of therapy depend upon the extent of iron deficiency. The daily dose can be divided into separate doses or can be taken at one time during or after meal.

Really Impaired Patients : Not known, administer with caution.

Packing :

Indications :

Female
Follicle Stimulation in IVF

Male
Infertile patients with oligoanovulation

Dosage :

Initail Dose : 225 Units

Male
Infertile patients with oligoanovulation : 150 Units daily for the first 5 days of treatment for patients who have received GnRH agonist or antagonist pitutary supression.

Renally Impaired Patients : Not known, administer with caution.

Packing : 

Acth-Biotech (Corticotrophin Carboxymethylcellulose Injection 73 300 IU)

Indications :

• Is indicated in conditions where a stimulatory effect of ACTH on the adrenal cortex is desired.

• Infantile spasm

• Bronchial Asthma

• Rheumotoid arithritis

• Multiple sclerosis

• Myasthenia gravis

• Ulcerative colitis

• Chronic active liver disease

• Hay fever

• Severe dermatitis

• Hemorrhage

• Collagen diseases

• Septicemia

• Nephrotic syndrome

• Severe stress conditions

• Adrenal function test

• Lupus erythematosus disseminatus

Dosage

It is preferable given SC but it may also be administered IM.

Long term treatment

Usual Dose : 15-30 IU (0.25-0.5ml) SC every two days for protracted treatment.
Max. Dose : 60IU (1ml) daily or every two days.
The same effect as with 15 IU daily is also achieved with 30 IU every two days or 60 IU twice weekly.
In severe dermatological disorders : 60 IU or more daily.
Infantile spasm : 20 IU IM daily for 2 weeks.
Max. Dose : 30 IU and then 40 IU IM for additional 4 weeks.

Short Term treatment

Multiple Sclerosis, Myasthenia Gravis and Ulcerative Colitis : The dosage in short term or initial treatment may vary considerably, daily dose of up to 120 IU (2ml) subcutaneously for intensive treatment.
Renally Impaired Patients : Administer with caution.

Packing : 5 Vials of 60 IU/ml

Indications:

• Acute Exacerbation Of Chronic Bronchitis
• Acute Bacterial Sinusitis
• Community Acquired Pneumonia
• Pharyngitis/Tonsillitis
• Uncomplicated SSTI
• Urethritis / Cervicitis
• Genital Ulcer Disease
• Acute Otitis Media
• Pevlic Inflammatory Diseases
• Sexually Transmitted Infections

Dosage :

Infants and Children : 10-30 mg/kg once a daily for 3 days.

Oral Dosage : 500 mg 3-4 times a day for 3-5 days.

Renally Impaired Patients : No dosage adjustment required.

Packing : 10 Strips of 6 Tablets

Indications :

• Intra-abdominal infections

• Urinary Tract Infections

• Septicemia

• Lower Respiratory Tract Infections

• Skin & soft tissue infections

• Bone & Joint infections

Dosage :

Adult : 500 mg to 2g every 8 or 12 hrs.

Maximum Dose : 8g/day.

Pediatric : 30–90 mg/kg every 6 – 8 hrs.

Maximum Dose : 120 mg/ kg/day.

Renally Impaired Patients : After an initial loading dose of 1 to 2 grams, the dose should be halved in patients with estimated creatinine clearance between 10 and 30 mL/min.

Packing : 10 Vials of 1000 mg

Indications :

• Constipation (Surgery, Pregnancy)

• Hepatic Encephalopathy

• Salmonellosis

• Renal Insufficiency

• Pre Surgical Evacunation, Diagnostic Aid

Dosage :

Adult : 15-30 ml 3-4 times a day.

Pediatric : 5-15 ml 1-2 times a day.

Hepatic Encephalopathy : Start with 30-40ml, 3 to 4 times daily.

Renally Impaired Patients : No dosage adjustment required.

Packing : 25 Bottles of 200 ml

(Cefuroxime Axetil Tablets USP 500 mg)

Indications :

• Upper Respiratory Tract Infections

• Uncomplicated urinary Tract Infections

• Uncomplicated skin & soft Tissue Infections

• Pharyngitis / tonsilitis
• Acute bacterial otitis media
• Acute bacterial maxillary sinusitis
• Acute bacterial exacerbation of chronic bronchitis & secondary bacterial infections of acute bronchitis
• Uncomplicated gonorrhea, urethral & endocervical

Dosage :  

Adult :

Oral : 250 mg to 500 mg BID for 10 days.

Paediatric : 30-100mg/kg/day BID / QID.

RenallyImpaired Patients :  

Oral

 Packing : 5 Strips of 4 Tablets

Indications :

• Upper Respiratory Tract Infections

• Urinary Tract Infections

• Skin & Soft Tissue Infections

• Bone & Joint Infections due to Saureus

Dosage :

Adult :

 Parenteral : 750 mg to 1.5 g every 8 hours for 5 to 10 days.

Oral : 250 mg to 500 mg BID for 10 days.

Paediatric : 30 - 100mg/kg/day BID / QID.

Renally Impaired Patients :

Oral

Packing : 10 Strips of 750 Tablets

Indications :

• Urinary Tract Infections.

• Lower Respiratory Tract Infections.

• Septicaemia, Bacteremia.

• Infections in Immunocompromised patients.

Dosage :

Adult : 1-2gm BID.

Paediatric : 10mg/kg BID.

Renally Impaired Patients :

  Packing : 10 Vials of 0.5 g

Choriotec (Chorionic Gonadotrophin For Injection BP 5000 IU0)

Indications :

Female :

• Anovulatory infertility
• Superovulation
• Corpus Luteum Insufficiency
• Habitual Abortion
• Threatened Abortion

Male :

• Hypogonadotropic hypogonadism
• Cryptorchidism
• Oligoasthenospermia
• Azoospermia

Dosage :

Female:

Anovulatory infertility : 5,000 I.U. or 10,000 I.U. given 24 - 48 hrs.

Superovulation : 10,000 IU of Choriotec is given in one single injection.

Corpus luteum Insufficiency : Up to 5000 I.U administered on the 5th day after ovulation and the same dose again on 9th day.

Habitual abortion / Threatened abortion :

Initial dose : 10,000 I.U.

Maintenance dose:
5000 I.U. twice weekly until (including) the 14th week of gestation.

MALE :

Hypogonadotropic/Hypogonadismm :Choriotec 2000 I.U. should be given 2-3 times per week.

Cryptorchidism :
Choriotec, 1000 I.U should be given on alternate days for several weeks .

Oligo-asthenospermia & azoospermia :
Choriotec 2000 I.U. should be given every 5 days and Menotec 75-150 I.U. 3 times a week for three months.

Renally Impaired Patients : Safety and efficacy not established.

Packing : 10 Vials of 5000 IU

(Amoxicillin And Clavulanate Potassium Tablets USP 375 mg)

Indications :

• Lower Respiratory Tract Infections
• Skin and Soft Tissue Infections
• Urinary Tract Infections
• Otitis media
• Sinusitis

Dosage :

Adult : 1000 mg tablet every 12 hrs. 625 mg tablet every 8 hrs.

Pediatric : 30 mg /kg in divided dose.

Oral Dosage : 375 mg 8-12 hourly.

Really Impaired Patients :

 Packing : 3 Strips of 6 Tablets

Clavox-New (Amoxicillin And Clavulanate Potassium Tablets USP 1000Mg)

Indications :

Lower Respiratory Tract Infections
Upper Respiratory Tract Infections
Skin and Soft Tissue Infections
Urinary Tract Infections

Dosage :

Adult :
1000 mg tablet every 12 hrs.
625 mg tablet every 8 hrs.

Pediatric : 30 mg /kg in divided dose.

Oral Dosage : 375 mg 8-12 hourly.

Really Impaired Patients :

Packing : 3 Strips of 4 Tablets

(Tramadol HCL 50mg Capsule)

Indications :  

Moderate to moderately severe pain. 

Dosage :  

Adults : 50 to 100mg can be administered as needed for pain relief every 4-6 hours not to exceed 400mg/day.

Paediatric : IV dose is1-2mg/kg. (Not recommended for infants below 2 yrs. Capsules and SR tablets are not recommended for use in children below the age of 12 years).

Renally impaired patients : In all patients with creatinine clearance less than 30 mL/min, it is recommended that the dosing interval should be increased to 12 hours, with a maximum daily dose of 200 mg. 

Packing : 1 Strip of 10 Caps.

Indications :

Moderate to moderately severe pain.

Dosage :

Adults : 50 to 100mg can be administered as needed for pain relief every 4-6 hours not to exceed 400mg/day.

Paediatric : IV dose is1-2mg/kg. (Not recommended for infants below 2 yrs. Capsules and SR tablets are not recommended for use in children below the age of 12 years).

Renally impaired patients : In all patients with creatinine clearance less than 30 mL/min, it is recommended that the dosing interval should be increased to 12 hours, with a maximum daily dose of 200 mg.

Packing : 1 Strip of 10 Tabs

Indications :

Moderate to moderately severe pain.

Dosage :

Adults : 50 to 100mg can be administered as needed for pain relief every 4-6 hours not to exceed 400mg/day.

Paediatric : IV dose is1-2mg/kg. (Not recommended for infants below 2 yrs. Capsules and SR tablets are not recommended for use in children below the age of 12 years).

Renally impaired patients : In all patients with creatinine clearance less than 30 mL/min, it is recommended that the dosing interval should be increased to 12 hours, with a maximum daily dose of 200 mg.

Packing : 1 Amp of 100 mg

(Ceftazidime Tazobactam: 1.125g Vials)

Indications :

• Lower Respiratory Tract Infections
• Skin and Skin Structure Infections
• Urinary Tract Infections
• Pelvic Inflammatory Disease
• Bacterial Septicemia
• Bone & Joint Infections
• Intra-Abdominal Infections & Central Nervous System Infections. 

Dosage :

Recommended maintenance doses of FORZID_TZ in adults with renal insufficiency

Packing : 1 Vial of 1.125g

Indications :

• Encephalopathy

• Acute Liver Failure

• Hyperammonemia due to liver cirrhosis, hepatitis, Fatty liver

• Jaundice

Dosage :

  Sachets : 1-2 Sachet (Dissolve in a glass of water) 3 times a day.

Renally Impaired Patients : Not known, administer with caution.

Packing : 10 Sachets of 5 g

Indications :

• Encephalopathy

• Acute Liver Failure

• Hyperammonemia due to liver cirrhosis, hepatitis, Fatty liver

• Jaundice

Dosage :

Injection
Adult : 4 amp. x 4 days or 8 amp. x 4 days and then 4 amp. x 3 days.

Maximum infusion rate : 5g / hr.

Renally Impaired Patients : Not known, administer with caution.

Packing : 5 Ampoules of 10 ml

Indications :

Bacterial septicaemia

• Peritonitis

• Skin and Soft tissue infections

• Pelvic Inflammatory disease

Dosage :

Adult :
2g to 4g/day in 2 equally divided doses.

Pediatric :
50-200 mg/kg/day in 2 equally divided doses.

Renally Impaired Patients : No dosage adjustment required.

Packing : 10 Vials of 1g

(Cefoperazone & Sulbactam 2g)

Indications : 

• Bacterial septicaemia

• Peritonitis

• Skin and Soft tissue infections

• Pelvic Inflammatory disease 

Dosage :  

Adult : 2g to 4g/day in 2 equally divided doses.

Pediatric: 50-200 mg/kg/day in 2 equally divided doses.

Renally Impaired Patients : No dosage adjustment required. 

Packing : 1 Vial of 2g

(Tobramycin 80mg Vials)

Indications : 

• Lower Respiratory Tract Infections.

• Complicated and recurrent UTIs.

• Intra abdominal infections.

• Septicaemia.

• Serious CNS infections.

• Nosocomial infections.
• Skin, bone & skin structure infections

Dosage :

Adult : 3-5 mg/kg daily in 3 or 4 divided dose.

Paediatric : 6-7.5 mg/kg/day in 3 or 4 divided dose.

Renally impaired patients :

High-dose (once daily) therapy:

 Packing : 1 Vial of 80mg

(Ofloxacin Tablets USP 200 mg)

Indications :

• Lower Respiratory infections
• Urinary Tract infections
• Uncomplicated skin and skin structure infection
• Sexually transmitted disease
• Prostatitis 

Dosage :  

Really Impaired Patients :  

Packing : 10 Strips of 10 Tablets

(Pantoprazole Tablets 40 mg)

Indications : 

• Erosive Esophagitis associated with gastroesophageal Reflux Disease (GERD)

• Zollinger Ellison Syndrome 

Dosage :

GERD : 40mg once daily upto 8 weeks.

Zollinger Ellison Syndrome : Starting dose is 40 mg twice daily. Doses should be adjusted according to patient. 

Erosive Esophagitis : 40mg taken daily. 

Packing : 10 Strips of 10 Tablets

(Ribavirin 200mg Capsule)

Indications : 

• Chronic Hepatitis B
• Chronic Hepatitis C virus
• In patients previously untreated with alpha interferon
• In patients who have relapsed following alpha interferon therapy 

Dosage :  

Ribavirin must be used in combination with either peginterferon alfa-2b or interferon alfa-2b.

The dose of Ribavirin is based on patient body weight.

Ribavirin capsules are to be administered orally each day in two divided doses (morning and evening) with food.

Adults : The dose of Ribapro is based on patient body weight.

Ribapro must be used in combination with either peginterferon alfa-2b (1.5 micrograms/kg/week) or interferon alfa-2b (3 million international units [MIU] three times a week). The choice of combination regimen is based on the characteristics of the patient. 

Children 3 years of age & older and adolescents : Dosing for children and adolescent patients is determined by body weight for Ribavirin and by body surface area for peginterferon alfa-2b and interferon alfa-2b. 

Packing : 1 Strip of 8 Caps.

(Cefixime Tablets USP 200 mg)

Indications :

• Upper Respiratory Tract Infections
• Lower Respiratory Tract Infections
• Uncomplicated Urinary Tract Infection
• Uncomplicated gnorrhea
• Otitis media

Dosage :  

Adult : 200-400mg/day as a single or in two divided doses.

Paediatric : 8mg/kg/ day as a single or in two divided doses.

Renally Impaired Patients :

Packing : 5 Strips of 4 Tablets

Indications :

• Prevention and symptomatic relief of acute nausea and vomiting from any cause including cytotoxic therapy, radio therapy and anti – parkinsonism

• Stimulation of gut mobility

• Non ulcer dyspepsia

• Esophageal reflux, Reflux Esophagitis and Gastritis

• Diabetic gastroparesis

• Functional dyspepsia

• Speeding barium transit in “follow – through” radiological studies

• In the treatment of migraine

Dosage :

Acute conditions (mainly nausea, vomiting, hiccup)
Adults : Two tablets (20 mg) 3 to 4 times per day.

Children 5 to 12 years old : One tablet (10 mg) 3 to 4 times per day.

Nausea / vomiting associated with dopamine agonist Anti – Parkinson agent :
20 mg 3-4 times / day.

Chronic conditions (mainly dyspepsia)
Adults : One tablet (10 mg) taken 3 times per day. The dosage may be doubled as per need.

Children 5 to 12 years old : ½ tablet (5 mg) 3 to 4 times per day.

Migraine : 20 mg every 4 hourly in combination with paracetamol.

Renally Impaired Patients : In patients with severe renal insufficiency (creatinine serum levels
> 6 mg/100mL, the elimination half-life of domperidone was increased from 7.4 to 20.8 hours. Administer with Caution.

  Packing : 10 Strips10 Tablets

(Iron Sucrose Injection USp 50mg / 2.5ml)

Indications : 

• Pre existing (moderate to severe) anemia

• Patients not responding or having poor compliance with oral iron supplements

• Pre and postoperative period

• Postpartum anemia and postpartum haemorrhage

• Patients with poor iron absorption (bowel operations or diseases)

• Patients with severe renal impairment 

Dosage :  

The total cumulative dose of iron sucrose, equivalent to the total iron deficit (mg), is determined by the hemoglobin level and body weight.

Adult : 100-200mg iron one-three times a week depending on the Hb level.

Children : 30mg/kg body wt. one-three times per week depending on the Hb level. 

Dosage Adjustment :

Renal Impairment : Administer with caution in severe renal impairment.

Hepatic Impairment : Required. 

Packing : 5 Ampoules of 2.5 ml

(Vasopressin 20 I.U. /  1ml Amp)

Indications : 

• Diabetes Insipidus

• Abdominal Distention

• Abdominal roentgenography 

Dosage :  

Adults :

Abdominal roentgenography : 2 Inj. of 10 Units (0.5ml) SC or IM

Abdominal Distention : 5 units (0.25 ml) initially, increase to 10 units (0.5 ml) to be given IM & repeat injection as required.

Diabetes Insipidus : 5- 10 units (0.25- 0.5 ml) IM/ SC 2-3 times daily.


Children :

Abdominal Distention : dosage to be reduced proportionately.

Diabetes Insipidus : 2.5- 10 units IM/ SC 2-4 times daily

Really impaired patients : Not known, administer with caution.

Hepatically impaired patients : Required, administer with caution. 

Packing : 5 Amp of 20 units / 1ml

(Voriconazole For Injection 200 mg)

Indications : 

• Invasive aspergillosis

• Candidemia

• Esophageal candidiasis

• Serious fungal infections caused by Scedosporium apiospermum 

Dosage :  

Paediatric (For age 2 to <12 years) : Not recommended for use in children below 2 years. 

 Paediatric (2-12 Years) : 

Renally Impaired Patients : No dosage adjustment required. 

Packing : 4 Vials of 200 mg